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ea0029p551 | Diabetes | ICEECE2012

Both β-cell dysfunction and insulin resistance are primary determinants of diabetes mellitus in patients with liver cirrhosis candidate to organ transplant

Grancini V , Lunati E , Boselli L , Masserini B , Zimbalatti D , Agnelli F , Bonadonna R , Beck-Peccoz P , Orsi E

Background: Impaired glucose (G) regulation (IGR) and diabetes mellitus (DM) are common in patients with liver cirrhosis. DM development has been associated to advanced liver disease (LD) and HCV infection. The relative roles played by insulin secretion and action, advanced LD and HCV infection in DM are somewhat unclear.Aim of the study: To assess in cirrhotic patients candidate to organ transplantation with no history of G abnormalities: i) prevalence ...

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ea0029p1180 | Obesity | ICEECE2012

Metabolic syndrome after liver transplantation: pre- and post-operative risk factors

Lunati M. , Grancini V. , Agnelli F. , Masserini B. , Zimbalatti D. , Rossi G. , Beck-Peccoz P. , Orsi E.

Background: Metabolic syndrome (MS) is a common condition among liver transplanted patients and it contributes to late morbidity and mortality by favoring the development of cardiovascular disease (CVD).The aim of this study was to assess the prevalence of MS in the first 6 months after orthotopic liver transplantation (OLT) and the associated pre-operative and post-operative risk factors.Methods: Seventy-one cirrhotic patients wer...

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Endocrine Abstracts

Both β-cell dysfunction and insulin resistance are primary determinants of diabetes mellitus in patients with liver cirrhosis candidate to organ transplant

Metabolic syndrome after liver transplantation: pre- and post-operative risk factors

BiosciAbstracts